Publications directly related to the project activity.
Song, Y., Rundberget, J.T., Evenseth, L.M., Xie, L., Gomes, T., Høgåsen, T., Iguchi, T., Tollefsen, K.E. Whole-organism transcriptomic analysis provides mechanistic insight into the acute toxicity of emamectin benzoate in Daphnia magna. Environ. Sci. Technol. DOI: 10.1021/acs.est.6b03456 (In press).
LaLone, C. A.; Villeneuve, D. L.; Lyons, D.; Helgen, H. W.; Robinson, S. L.; Swintek, J. A.; Saari, T. W.; Ankley, G. T., (2016) Editor's Highlight: Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS): A web-based tool for addressing the challenges of cross-species extrapolation of chemical toxicity. Toxicol. Sci. 153, (2), 228-45.
Sumiya, E., Ogino, Y., Toyota, K., Miyakawa, H., Miyagawa, S. and Iguchi, T. (2016). Neverland regulates embryonic moltings through the regulation of ecdysteroid synthesis in the water flea Daphnia magna, and may thus act as a target for chemical disruption of molting. J. Appl. Toxicol., 36(11):1476-85.
Abe, R.; Toyota, K.; Miyakawa, H.; Watanabe, H.; Oka, T.; Miyagawa, S.; Nishide, H.; Uchiyama, I.; Tollefsen, K. E.; Iguchi, T.; Tatarazako, N., Diofenolan induces male offspring production through binding to the juvenile hormone receptor in Daphnia magna. Aquat. Toxicol. 2015, 159, 44-51.
Toyota, K., Miyakawa, H., Yamaguchi, K., Shigenobu, S., Ogino, Y., Tatarazako, N., Miyagawa, S. and Iguchi, T. (2015). NMDA receptor activation on the upstream of methyl farnesoate signaling for short-day induced male offspring production in water flea Daphnia pulex. BMC Genomics, 16, 186.
Toyota, K., Miyakawa, H., Hiruta, C., Furuta, K., Ogino, Y., Shinoda, T., Tatarazako, N., Miyagawa, S., Shaw, J.R. and Iguchi, T. (2015). Methyl farnesoate synthesis is necessary for the environmental sex determination in the water flea Daphnia pulex. J. Insect Physiol., 80, 22-30.
Groh, K.J., Tollefsen, K.E. (2015) The Challenge: Adverse outcome pathways in research and regulation-Current status and future perspectives. Environ Toxicol Chem. 34(9):1935.
Evenseth, L.M. (2014). Structure, function and ligand interactions of the ecdysone receptor from Daphnia magna, Master thesis in Molecular Biotechnology, UiT The Arctic University of Norway, June 2014.
Mellor C, Cronin M, Evenseth L, Sylte I, Kristiansen K, Tollefsen KE. Integrating computational modelling of receptor binding into mechanistically based risk assessment for endocrine disruptors. Toxicology Letters 2014; 229: S162-S163.
Sumiya, E., Ogino Y., Miyakawa, H., Hiruta, C., Toyota, K., Miyagawa, S. and Iguchi, T. (2014). Roles of ecdysteroids for progression of reproductive cycle in the fresh water crustacean Daphnia magna. Front. Zool., 11, 60.
Papers coming out from the AOP Workshop (2014)
Garcia-Reyero N. Are adverse outcome pathways here to stay? Environmental Science & Technology 2015; 49: 3-9.
Tollefsen KE, Scholz S, Cronin MT, Edwards SW, de Knecht J, Crofton K, et al. Applying Adverse Outcome Pathways (AOPs) to support Integrated Approaches to Testing and Assessment (IATA). Regulatory Toxicology and Pharmacology 2014; 70: 629-640.
Villeneuve DL, Crump D, Garcia-Reyero N, Hecker M, Hutchinson TH, LaLone CA, et al. Adverse outcome pathway (AOP) development I: strategies and principles. Toxicol Sci 2014; 142: 312-20.
Villeneuve DL, Crump D, Garcia-Reyero N, Hecker M, Hutchinson TH, LaLone CA, et al. Adverse outcome pathway development II: best practices. Toxicol Sci 2014; 142: 321-30.
Groh KJ, Carvalho RN, Chipman JK, Denslow ND, Halder M, Murphy CA, et al. Development and application of the adverse outcome pathway framework for understanding and predicting chronic toxicity: I. Challenges and research needs in ecotoxicology. Chemosphere 2015; 120: 764-777.
Groh KJ, Carvalho RN, Chipman JK, Denslow ND, Halder M, Murphy CA, et al. Development and application of the adverse outcome pathway framework for understanding and predicting chronic toxicity: II. A focus on growth impairment in fish. Chemosphere 2015; 120: 778-92.