Publications

Publications directly related to the project activity.

Evenseth, L.M. (2014). Structure, function and ligand interactions of the ecdysone receptor from Daphnia Magna, Master thesis in Molecular Biotechnology, UiT The Arctic University of Norway, June 2014.

Mellor, C.L., Cronin, M.T., Evenseth, L.M., Sylte, I., Kristiansen, K., Tollefsen, K.E. (2014). Integrating Computational Modelling of Receptor Binding into Mechanistically-Based Risk Assessment for Endocrine Disruptors. Toxicology Letters 229, Supplement(0): S162-S163. http://dx.doi.org/10.1016/j.toxlet.2014.06.559.

Sumiya, E., Ogino Y., Miyakawa, H., Hiruta, C., Toyota, K., Miyagawa, S. and Iguchi, T. (2014). Roles of ecdysteroids for progression of reproductive cycle in the fresh water crustacean Daphnia magna. Front. Zool., 11, 60.

Abe, R, Toyota, K., Miyakawa, H., Watanabe,H., Okad, T., Miyagaw, S. Nishide, H., Uchiyamae, I., Tollefsen, K.E., Iguchi, T., Tatarazakoa, N. (In review process) Comparison between TG211 ANNEX 7 and short-term screening assay for detecting male offspring production in Daphnia magna using diofenolan. Aquatic toxicology.

 

Papers produced from the the AOP Workshop (2014)

Garcia-Reyero N. (2014) Living the adverse outcome pathway revolution. Environ Sci Technol. 2014. Feature article. In preparation.

Tollefsen K.E., Scholz S., Cronin, M., Edwards, S., de Knecht, J., Crofton, K., Garcia-Reyero, N, Hartung T., Worth, A., Patlewicz, G. (In press). Applying adverse outcome pathways to support integrated approaches to testing and assessment. Reg Tox Pharm. 2014.

Villeneuve, D. L., Crump, D., Garcia-Reyero, N., Hecker, M., Hutchinson, T. H., LaLone, C. A., Landesmann, B., Lettieri, T., Munn, S., Nepelska, M., Ottinger, M. A., Vergauwen, L., Whelan, M. (In press). Adverse outcome pathway (AOP) development I: strategies and principles. Toxicol. Sci. (DOI: 10.1093/toxsci/kfu199).

Villeneuve, D. L., Crump, D., Garcia-Reyero, N., Hecker, M., Hutchinson, T. H., LaLone, C. A., Landesmann, B., Lettieri, T., Munn, S., Nepelska, M., Ottinger, M. A., Vergauwen, L., Wehlan, M. (In press). Adverse outcome pathway (AOP) development II: best practices. Toxicol. Sci. (DOI: 10.1093/toxsci/kfu200).

Ksenia J. Groh, Raquel N. Carvalho, J. Kevin Chipman, Nancy D. Denslow, Marlies Halder, Cheryl A. Murphy, Dick Roelofs, Alexandra Rolaki, Kristin Schirmer, Karen H. Watanabe. (Submitted). Development and application of the adverse outcome pathway framework for understanding and predicting chronic toxicity: I. Challenges and research needs in ecotoxicology. Chemosphere. 2014.

Ksenia J. Groh, Raquel N. Carvalho, J. Kevin Chipman, Nancy D. Denslow, Marlies Halder, Cheryl A. Murphy, Dick Roelofs, Alexandra Rolaki, Kristin Schirmer, Karen H. Watanabe (Submitted). Development and application of the adverse outcome pathway framework for understanding and predicting chronic toxicity: II. A focus on growth impairment in fish. Chemosphere. 2014.

Tara Barton-Maclaren, Rick Becker, Bart Van Der Burg, Sean Kennedy, Bette Meek, Gary Ankley, Igor Linkov, Helmut Segner, Haruna Watanabe, Magdalini Sachana, Dan Villeneuve, Stephen Edwards (In prep.). Weight of Evidence evaluation based on the evolved Bradford Hill considerations to define confidence associated with predictive relationships represented in an AOP.

Perkins EJ, Antczak P, Burgoon L, Falciani F, Garcia-Reyero N, Gutsell S, Hodges G, Kienzler A, Knapen D, McBride M, Willett C. (In prep.) Using adverse outcome pathways for regulatory applications. ToxSci. 2014.

 

Sist oppdatert 09.02.2015