Knut Erik Tollefsen
dr.scient. (PhD)
Position: Chief Scientist
Phone: +47 922 18 466
Section: Økotoksikologi og risikovurdering
Dr. Knut Erik Tollefsen, senior scientist at Section for ecotoxicology and risk assessment has been employed at Norwegian Institute for water research (NIVA) since January 2002. He is alos workng as an Adjunct Professor in Ecotoxicology at Norwegian University of Life Sciences (NMBU) since Aug. 2006. He is an Eurotox registered ecotoxicologist with over 20 years of experience in ecotoxicology with special emphasis on ecotoxicological testing (effect assessment), biomarker research, ecotoxicogenomics, environmental monitoring, endocrine disruption, radiation, combined toxicity and risk assessment. Dr. Tollefsen is acting as an expert advisor for the Norwegian Environment Agency; participates in the OECD working and management group on non-animal testing (WMG-NA), the OECD advisory group on Molecular Screening and Toxicogenomics (EAGMST) and the EC expert advisory group on endocrine disruptors. He has extensive project management experience in national and international projects and has published over 120 scientific papers in peer-reviewed journals (h-index:37, i10-index: 74), supervised 6 Bc. Sc. students, 17 M. Sc. students, 20 PhD. students and 5 Post docs.

Use the tab and enter or arrow keys to move between tabs

Scientific articles and Bookchapters

  1. Cao, Yang; Moe, Jannicke; De Bin, Riccardo; Tollefsen, Knut-Erik; Song, You; (2022) Comparison of structural equation modeling and Bayesian network for de novo construction of a quantitative adverse outcome pathway network. Altex ISSN 1868-596X. doi: 10.14573/altex.2207113
  2. Burtt, Julie J.; Leblanc, Julie; Randhawa, Kristi; Ivanova, Addie; Rudd, Murray A.; Wilkins, Ruth; Azzam, Edouard I.; Hecker, Markus; Horemans, Nele; Vandenhove, Hildegarde; Adam-Guillermin, Christelle; Armant, Olivier; Klokov, Dmitry; Audouze, Karine; Kaiser, Jan Christian; Moertl, Simone; Lumniczky, Katalin; Tanaka, Ignacia B.; Yamada, Yutaka; Hamada, Nobuyuki; Al-Nabulsi, Isaf; Preston, R. Julian; Bouffler, Simon; Applegate, Kimberly; Cool, Donald; Beaton, Danielle; Tollefsen, Knut-Erik; Garnier-Laplace, Jacqueline; Laurier, Dominique; Chauhan, Vinita; (2022) Radiation adverse outcome pathways (AOPs) are on the horizon: Advancing radiation protection through an international Horizon-Style exercise. International Journal of Radiation Biology ISSN 0955-3002. Vol 98 No12 s1763-1776 doi: 10.1080/09553002.2022.2121439
  3. Chauhan, Vinita; Hamada, Nobuyuki; Wilkins, Ruth; Garnier-Laplace, Jacqueline; Laurier, Dominique; Beaton, Danielle; Tollefsen, Knut-Erik; (2022) A high-level overview of the OECD AOP Development Programme. International Journal of Radiation Biology ISSN 0955-3002. Vol 98 No12 s1704-1713 doi: 10.1080/09553002.2022.2110311
  4. Tollefsen, Knut Erik; Alonzo, Frederic; Beresford, Nicholas A.; Brede, Dag Anders; Dufourcq-Sekatcheff, Elizabeth; Gilbin, Rodolphe; Horemans, Nele; Hurem, Selma; Laloi, Patrick; Maremonti, Erica; Oughton, Deborah Helen; Simon, Olivier; Song, You; Wood, Michael; Xie, Li; Frelon, Sandrine; (2022) Adverse outcome pathways (AOPs) for radiation-induced reproductive effects in environmental species: state of science and identification of a consensus AOP network. International Journal of Radiation Biology ISSN 0955-3002. Vol 98 No12 s1816-1831 doi: 10.1080/09553002.2022.2110317
  5. Toyota, Kenji; Watanabe, Haruna; Hirano, Masashi; Abe, Ryoko; Miyakawa, Hitoshi; Song, You; Sato, Tomomi; Miyagawa, Shinichi; Tollefsen, Knut-Erik; Yamamoto, Hiroshi; Tatarazako, Norihisa; Iguchi, Taisen; (2022) Juvenile hormone synthesis and signaling disruption triggering male offspring induction and population decline in cladocerans (water flea): Review and adverse outcome pathway development. Aquatic Toxicology ISSN 0166-445X. Vol 243 doi: 10.1016/j.aquatox.2021.106058
  6. Xie, Li; Song, You; Petersen, Karina; Solhaug, Knut Asbjørn; Lind, Ole Christian; Brede, Dag Anders; Salbu, Brit; Tollefsen, Knut-Erik; (2022) Ultraviolet B modulates gamma radiation-induced stress responses in Lemna minor at multiple levels of biological organisation. Science of the Total Environment ISSN 0048-9697. Vol 846 doi: 10.1016/j.scitotenv.2022.157457
  7. Mentzel, Sophie; Grung, Merete; Holten, Roger; Tollefsen, Knut-Erik; Stenrød, Marianne; Moe, S. Jannicke; (2022) Probabilistic risk assessment of pesticides under future agricultural and climate scenarios using a bayesian network. Frontiers in Environmental Science ISSN 2296-665X. Vol 10 s1-17 doi: 10.3389/fenvs.2022.957926
  8. Mentzel, Sophie; Grung, Merete; Holten, Roger; Tollefsen, Knut-Erik; Stenrød, Marianne; Moe, S. Jannicke; (2022) Probabilistic risk assessment of pesticides under future agricultural and climate scenarios using a bayesian network. Frontiers in Environmental Science ISSN 2296-665X. Vol 10 s1-17 doi: 10.3389/fenvs.2022.957926
  9. Beyer, Jonny; Song, You; Tollefsen, Knut-Erik; Berge, John Arthur; Tveiten, Lise Ann; Helland, Aud; Øxnevad, Sigurd; Schøyen, Merete; (2022) The ecotoxicology of marine tributyltin (TBT) hotspots: A review. Marine Environmental Research ISSN 0141-1136. Vol 179 doi: 10.1016/j.marenvres.2022.105689
  10. Xie, Li; Macken, Ailbhe; Johnsen, Bjørn; Norli, Marit; Skogan, Odd Arne Segtnan; Tollefsen, Knut-Erik; (2022) The MicroClimate Screen – A microscale climate exposure system for assessing the effect of CO<inf>2</inf>, temperature and UV on marine microalgae. Marine Environmental Research ISSN 0141-1136. Vol 179 doi: 10.1016/j.marenvres.2022.105670
  11. Jaylet, Thomas; Quintens, Roel; Benotmane, Mohamed Abderrafi; Luukkonen, Jukka; Tanaka, Ignacia Braga; Ibanez, Chrystelle; Durand, Christelle; Sachana, Magdalini; Azimzadeh, Omid; Adam-Guillermin, Christelle; Tollefsen, Knut-Erik; Laurent, Olivier; Audouze, Karine; Armant, Olivier; (2022) Development of an adverse outcome pathway for radiation-induced microcephaly via expert consultation and machine learning. International Journal of Radiation Biology ISSN 0955-3002. Vol 98 No12 s1752-1762 doi: 10.1080/09553002.2022.2110312
  12. Cao, Yang; Moe, S. Jannicke; De Bin, Riccardo; Tollefsen, Knut-Erik; Song, You; (2022) Comparison of structural equation modeling and Bayesian network for de novo construction of a quantitative adverse outcome pathway network. Altex ISSN 1868-596X. doi: 10.14573/altex.2207113
  13. Scheibener, Shane; Song, You; Tollefsen, Knut-Erik; Salbu, Brit; Teien, Hans-Christian; (2021) Uranium accumulation and toxicokinetics in the crustacean Daphnia magna provide perspective to toxicodynamic responses. Aquatic Toxicology ISSN 0166-445X. Vol 235 doi: 10.1016/j.aquatox.2021.105836
  14. Schmid, Simon; Song, You; Tollefsen, Knut Erik; (2021) AOP report: Inhibition of chitin synthase 1 leading to increased mortality in arthropods. Environmental Toxicology and Chemistry ISSN 0730-7268. Vol 40 No8 s2112-2120 doi: 10.1002/etc.5058
  15. Wolf, Raoul; Tollefsen, Knut-Erik; (2021) A Bayesian approach to incorporating spatiotemporal variation and uncertainty limits into modeling of predicted environmental concentrations from chemical monitoring campaigns. Environmental Science and Technology ISSN 0013-936X. Vol 55 No3 s1699-1709 doi: 10.1021/acs.est.0c06268
  16. Lerebours, Adélaïde; Murzina, Svetlana; Song, You; Tollefsen, Knut-Erik; Benedetti, Maura; Regoli, Francesco; Rotchell, Jeanette M.; Nahrgang, Jasmine; (2021) Susceptibility of polar cod (Boreogadus saida) to a model carcinogen. Marine Environmental Research ISSN 0141-1136. Vol 170 doi: 10.1016/j.marenvres.2021.105434
  17. Mentzel, Sophie; Grung, Merete; Tollefsen, Knut-Erik; Stenrød, Marianne; Petersen, Karina; Moe, S. Jannicke; (2021) Development of a Bayesian network for probabilistic risk assessment of pesticides. Integrated Environmental Assessment and Management ISSN 1551-3777. doi: 10.1002/ieam.4533
  18. Myklebust, Erik Bryhn; Jimenez-Ruiz, Ernesto; Chen, Jiaoyan; Wolf, Raoul; Tollefsen, Knut Erik; (2021) Prediction of adverse biological effects of chemicals using knowledge graph embeddings. Semantic Web Journal ISSN 1570-0844. Vol 13 No3 s299-338 doi: 10.3233/SW-222804
  19. Toyota, Kenji; Watanabe, Haruna; Hirano, Masashi; Abe, Ryoko; Miyakawa, Hitoshi; Song, You; Sato, Tomomi; Miyagawa, Shinichi; Tollefsen, Knut Erik; Yamamoto, Hiroshi; Tatarazako, Norihisa; Iguchi, Taisen; (2021) Juvenile hormone synthesis and signaling disruption triggering male offspring induction and population decline in cladocerans (water flea): Review and adverse outcome pathway development. Aquatic Toxicology ISSN 0166-445X. Vol 243 doi: 10.1016/j.aquatox.2021.106058
  20. Song, You; Xie, Li; Lee, YeonKyeong; Tollefsen, Knut Erik; (2020) De novo Development of a Quantitative Adverse Outcome Pathway (qAOP) Network for Ultraviolet B (UVB) Radiation Using Targeted Laboratory Tests and Automated Data Mining. Environmental Science and Technology ISSN 0013-936X. Vol 54 No20 s13147-13156 doi: 10.1021/acs.est.0c03794
NIVA began to register scientific articles in CRIStin in 2010, reports from 2014.

Reports

Other